feat: add data objects

.gitignore

@@ -0,0 +1 @@
+**/.DS_Store

processed/inductive/test_df.csv

@@ -0,0 +1,2433 @@
+hyperedge,nodes,timestamp
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raw/DATA-DESCRIPTION.txt

@@ -0,0 +1,44 @@
+Each timestamped simplex dataset consists of three files:
+1. dataset-nverts.txt
+2. dataset-simplices.txt
+3. dataset-times.txt
+
+All three files represent a vector of integers. There is one integer per line.
+
+The first file contains the number of vertices within each simplex. The second
+file is a contiguous list of the nodes comprising the simplices, where the
+ordering of the simplices is the same as in the first file. The third file
+contains the timestamps for each simplex. The length of the vectors in the first
+and third files is the same, and the length of the vector in the second file is
+the sum of the integers in the first file.
+
+Consider an example dataset consisting of three simplices:
+1. {1, 2, 3} at time 10
+2. {2, 4} at time 15.
+3. {1, 3, 4, 5} at time 21.
+Then files would look as follows:
+
+example-nverts.txt
+3
+2
+4
+
+example-simplices.xt
+1
+2
+3
+2
+4
+1
+3
+4
+5
+
+example-times.txt
+10
+15
+21
+
+
+
+For problems, please contact Austin Benson at arb@cs.cornell.edu.

raw/NDC-classes-full-node-labels.txt

@@ -0,0 +1,1161 @@
+1 radioactive diagnostic agent [epc]
+2 positron emitting activity [moa]
+3 antiarrhythmic [epc]
+4 cytochrome p450 2d6 inhibitor [epc]
+5 cytochrome p450 2d6 inhibitors [moa]
+6 glp-1 receptor agonist [epc]
+7 glucagon-like peptide 1 [chemical/ingredient]
+8 glucagon-like peptide-1 (glp-1) agonists [moa]
+9 interleukin-17a antagonist [epc]
+10 interleukin-17a antagonists [moa]
+11 androgen [epc]
+12 androgen receptor agonists [moa]
+13 androstanes [chemical/ingredient]
+14 serotonin reuptake inhibitor [epc]
+15 serotonin uptake inhibitors [moa]
+16 norepinephrine reuptake inhibitor [epc]
+17 norepinephrine uptake inhibitors [moa]
+18 atypical antipsychotic [epc]
+19 serotonin and norepinephrine reuptake inhibitor [epc]
+20 estrogen agonist/antagonist [epc]
+21 selective estrogen receptor modulators [moa]
+22 phosphodiesterase 5 inhibitor [epc]
+23 phosphodiesterase 5 inhibitors [moa]
+24 decreased platelet aggregation [pe]
+25 p2y12 platelet inhibitor [epc]
+26 p2y12 receptor antagonists [moa]
+27 nucleic acid synthesis inhibitors [moa]
+28 nucleoside metabolic inhibitor [epc]
+29 insulin [chemical/ingredient]
+30 insulin analog [epc]
+31 folate analog metabolic inhibitor [epc]
+32 folic acid metabolism inhibitors [moa]
+33 vascular endothelial growth factor receptor 2 antagonist [epc]
+34 vegfr2 inhibitors [moa]
+35 epidermal growth factor receptor antagonist [epc]
+36 her1 antagonists [moa]
+37 parathyroid hormone [chemical/ingredient]
+38 parathyroid hormone analog [epc]
+39 insulin [epc]
+40 hepatitis c virus ns5a inhibitor [epc]
+41 p-glycoprotein inhibitors [moa]
+42 organic anion transporting polypeptide 1b1 inhibitors [moa]
+43 organic anion transporting polypeptide 1b3 inhibitors [moa]
+44 breast cancer resistance protein inhibitors [moa]
+45 corticosteroid [epc]
+46 corticosteroid hormone receptor agonists [moa]
+47 t lymphocyte costimulation activity blockade [pe]
+48 selective t cell costimulation blocker [epc]
+49 cd80-directed antibody interactions [moa]
+50 cd86-directed antibody interactions [moa]
+51 kinase inhibitor [epc]
+52 protein kinase inhibitors [moa]
+53 cytochrome p450 3a4 inhibitors [moa]
+54 antimetabolite [epc]
+55 urea [chemical/ingredient]
+56 factor xa inhibitor [epc]
+57 factor xa inhibitors [moa]
+58 hepatitis b virus nucleoside analog reverse transcriptase inhibitor [epc]
+59 nucleoside analog [chemical/ingredient]
+60 nucleoside reverse transcriptase inhibitors [moa]
+61 human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor [epc]
+62 decreased cytokine activity [pe]
+63 selective t cell costimulation modulator [epc]
+64 recombinant fusion proteins [chemical/ingredient]
+65 monobactam antibacterial [epc]
+66 monobactams [chemical/ingredient]
+67 slamf7-directed immunostimulatory antibody [epc]
+68 slamf7-directed antibody interactions [moa]
+69 antibodies
+70 monoclonal [chemical/ingredient]
+71 ctla-4-directed blocking antibody [epc]
+72 ctla-4-directed antibody interactions [moa]
+73 increased t lymphocyte activation [pe]
+74 hiv protease inhibitors [moa]
+75 protease inhibitor [epc]
+76 ugt1a1 inhibitors [moa]
+77 udp glucuronosyltransferases inhibitors [moa]
+78 cytochrome p450 3a inhibitors [moa]
+79 cytochrome p450 2c8 inhibitors [moa]
+80 cytochrome p450 3a inhibitor [epc]
+81 programmed death receptor-1 blocking antibody [epc]
+82 programmed death receptor-1-directed antibody interactions [moa]
+83 hmg-coa reductase inhibitor [epc]
+84 hydroxymethylglutaryl-coa reductase inhibitors [moa]
+85 cytomegalovirus nucleoside analog dna polymerase inhibitor [epc]
+86 dna polymerase inhibitors [moa]
+87 nucleoside analog antiviral [epc]
+88 benzodiazepine [epc]
+89 benzodiazepines [chemical/ingredient]
+90 bisphosphonate [epc]
+91 diphosphonates [chemical/ingredient]
+92 intestinal lipase inhibitor [epc]
+93 lipase inhibitors [moa]
+94 antimetabolite immunosuppressant [epc]
+95 interferon alpha [epc]
+96 peginterferon alfa-2a [chemical/ingredient]
+97 erythropoiesis-stimulating agent [epc]
+98 erythropoietin [chemical/ingredient]
+99 increased erythroid cell production [pe]
+100 cyclooxygenase inhibitors [moa]
+101 nonsteroidal anti-inflammatory compounds [chemical/ingredient]
+102 nonsteroidal anti-inflammatory drug [epc]
+103 inactivated pneumococcal vaccine [epc]
+104 actively acquired immunity [pe]
+105 vaccines
+106 inactivated [chemical/ingredient]
+107 pneumococcal vaccines [chemical/ingredient]
+108 conjugate [chemical/ingredient]
+109 orexin receptor antagonist [epc]
+110 orexin receptor antagonists [moa]
+111 angiotensin converting enzyme inhibitor [epc]
+112 angiotensin-converting enzyme inhibitors [moa]
+113 antiparasitic [epc]
+114 pediculicide [epc]
+115 5-alpha reductase inhibitor [epc]
+116 5-alpha reductase inhibitors [moa]
+117 dipeptidyl peptidase 4 inhibitor [epc]
+118 dipeptidyl peptidase 4 inhibitors [moa]
+119 biguanide [epc]
+120 biguanides [chemical/ingredient]
+121 hiv integrase inhibitors [moa]
+122 human immunodeficiency virus integrase strand transfer inhibitor [epc]
+123 serotonin 1b receptor agonists [moa]
+124 serotonin 1d receptor agonists [moa]
+125 serotonin-1b and serotonin-1d receptor agonist [epc]
+126 vitamin d [chemical/ingredient]
+127 vitamin d [epc]
+128 protease-activated receptor-1 antagonist [epc]
+129 protease-activated receptor-1 antagonists [moa]
+130 neurokinin 1 antagonists [moa]
+131 substance p/neurokinin-1 receptor antagonist [epc]
+132 cytochrome p450 2c9 inducers [moa]
+133 cytochrome p450 3a4 inducers [moa]
+134 histone deacetylase inhibitor [epc]
+135 histone deacetylase inhibitors [moa]
+136 angiotensin 2 receptor antagonists [moa]
+137 angiotensin 2 receptor blocker [epc]
+138 increased diuresis [pe]
+139 thiazide diuretic [epc]
+140 thiazides [chemical/ingredient]
+141 leukotriene receptor antagonist [epc]
+142 leukotriene receptor antagonists [moa]
+143 hcv ns3/4a protease inhibitors [moa]
+144 hepatitis c virus ns3/4a protease inhibitor [epc]
+145 dipeptidase inhibitors [moa]
+146 renal dehydropeptidase inhibitor [epc]
+147 carbapenems [chemical/ingredient]
+148 penem antibacterial [epc]
+149 carbonic anhydrase inhibitor [epc]
+150 carbonic anhydrase inhibitors [moa]
+151 echinocandin antifungal [epc]
+152 lipopeptides [chemical/ingredient]
+153 aromatic amino acid [epc]
+154 amino acids
+155 aromatic [chemical/ingredient]
+156 inactivated human papillomavirus vaccine [epc]
+157 papillomavirus vaccines [chemical/ingredient]
+158 live rotavirus vaccine [epc]
+159 rotavirus vaccines [chemical/ingredient]
+160 live
+161 unattenuated [chemical/ingredient]
+162 inactivated hepatitis b virus vaccine [epc]
+163 hepatitis b vaccines [chemical/ingredient]
+164 inactivated hepatitis a virus vaccine [epc]
+165 hepatitis a vaccines [chemical/ingredient]
+166 live attenuated measles virus vaccine [epc]
+167 attenuated [chemical/ingredient]
+168 measles vaccine [chemical/ingredient]
+169 live attenuated mumps virus vaccine [epc]
+170 mumps vaccine [chemical/ingredient]
+171 live attenuated rubella virus vaccine [epc]
+172 rubella vaccine [chemical/ingredient]
+173 live attenuated varicella zoster virus vaccine [epc]
+174 chickenpox vaccine [chemical/ingredient]
+175 live attenuated herpes zoster virus vaccine [epc]
+176 herpes zoster vaccine [chemical/ingredient]
+177 standardized pollen allergenic extract [epc]
+178 increased histamine release [pe]
+179 cell-mediated immunity [pe]
+180 increased igg production [pe]
+181 pollen [chemical/ingredient]
+182 allergens [chemical/ingredient]
+183 tumor necrosis factor blocker [epc]
+184 tumor necrosis factor receptor blocking activity [moa]
+185 inactivated haemophilus influenzae b vaccine [epc]
+186 haemophilus vaccines [chemical/ingredient]
+187 gamma-cyclodextrins [chemical/ingredient]
+188 adrenergic alpha-antagonists [moa]
+189 adrenergic beta1-antagonists [moa]
+190 adrenergic beta2-antagonists [moa]
+191 alpha-adrenergic blocker [epc]
+192 beta-adrenergic blocker [epc]
+193 decreased renal k+ excretion [pe]
+194 potassium-sparing diuretic [epc]
+195 topoisomerase inhibitor [epc]
+196 topoisomerase inhibitors [moa]
+197 anti-coagulant [epc]
+198 direct thrombin inhibitor [epc]
+199 thrombin inhibitors [moa]
+200 increased megakaryocyte maturation [pe]
+201 increased platelet production [pe]
+202 thrombopoietin receptor agonist [epc]
+203 thrombopoietin receptor agonists [moa]
+204 ugt1a3 inhibitors [moa]
+205 ugt1a4 inhibitors [moa]
+206 ugt1a6 inhibitors [moa]
+207 ugt1a9 inhibitors [moa]
+208 ugt2b7 inhibitors [moa]
+209 ugt2b15 inhibitors [moa]
+210 dopamine agonists [moa]
+211 nonergot dopamine agonist [epc]
+212 vinca alkaloid [epc]
+213 vinca alkaloids [chemical/ingredient]
+214 proton pump inhibitor [epc]
+215 proton pump inhibitors [moa]
+216 decreased immunologic activity [pe]
+217 mtor inhibitor immunosuppressant [epc]
+218 mtor inhibitors [moa]
+219 estrogen [epc]
+220 estrogen receptor agonists [moa]
+221 estrogens
+222 conjugated (usp) [chemical/ingredient]
+223 antimycobacterial [epc]
+224 cd33-directed cytotoxin [epc]
+225 tetracycline-class antibacterial [epc]
+226 tetracyclines [chemical/ingredient]
+227 progesterone congeners [chemical/ingredient]
+228 progestin [epc]
+229 decreased sebaceous gland activity [pe]
+230 lincosamide antibacterial [epc]
+231 lincosamides [chemical/ingredient]
+232 decreased cell wall synthesis & repair [pe]
+233 bile acid sequestrant [epc]
+234 bile-acid binding activity [moa]
+235 estradiol congeners [chemical/ingredient]
+236 sulfonylurea [epc]
+237 sulfonylurea compounds [chemical/ingredient]
+238 prostaglandin analog [epc]
+239 prostaglandins [chemical/ingredient]
+240 genitourinary arterial vasodilation [pe]
+241 prostaglandin e1 agonist [epc]
+242 prostaglandin receptor agonists [moa]
+243 venous vasodilation [pe]
+244 cholinergic muscarinic antagonist [epc]
+245 cholinergic muscarinic antagonists [moa]
+246 oxazolidinone antibacterial [epc]
+247 oxazolidinones [chemical/ingredient]
+248 alpha glucosidase inhibitors [moa]
+249 alpha-glucosidase inhibitor [epc]
+250 anthracycline topoisomerase inhibitor [epc]
+251 anthracyclines [chemical/ingredient]
+252 cholinergic nicotinic agonist [epc]
+253 nicotine [chemical/ingredient]
+254 immunoglobulin g [epc]
+255 lymphocyte function alteration [pe]
+256 increased t lymphocyte destruction [pe]
+257 antibody-surface protein interactions [moa]
+258 immunoglobulins [chemical/ingredient]
+259 aromatase inhibitor [epc]
+260 aromatase inhibitors [moa]
+261 aminosalicylate [epc]
+262 aminosalicylic acids [chemical/ingredient]
+263 alkylating activity [moa]
+264 alkylating drug [epc]
+265 estradiol [chemical/ingredient]
+266 nitrogen mustard compounds [chemical/ingredient]
+267 antifibrinolytic agent [epc]
+268 decreased fibrinolysis [pe]
+269 rifamycin antimycobacterial [epc]
+270 rifamycins [chemical/ingredient]
+271 cytoprotective agent [epc]
+272 radiographic contrast agent [epc]
+273 x-ray contrast activity [moa]
+274 gadolinium-based contrast agent [epc]
+275 magnetic resonance contrast activity [moa]
+276 osmotic laxative [epc]
+277 increased large intestinal motility [pe]
+278 inhibition large intestine fluid/electrolyte absorption [pe]
+279 osmotic activity [moa]
+280 retinoid [epc]
+281 retinoids [chemical/ingredient]
+282 aminoglycoside antibacterial [epc]
+283 aminoglycosides [chemical/ingredient]
+284 sulfonamide antibacterial [epc]
+285 sulfonamides [chemical/ingredient]
+286 acetylcholine release inhibitor [epc]
+287 acetylcholine release inhibitors [moa]
+288 cyclooxygenase inhibitor [epc]
+289 quinolone antimicrobial [epc]
+290 quinolones [chemical/ingredient]
+291 sulfone [epc]
+292 sulfones [chemical/ingredient]
+293 histamine h1 receptor antagonists [moa]
+294 histamine-1 receptor antagonist [epc]
+295 adrenergic beta-antagonists [moa]
+296 antiprotozoal [epc]
+297 decarboxylase inhibitor [epc]
+298 decarboxylase inhibitors [moa]
+299 vasoconstrictor [epc]
+300 vasoconstriction [pe]
+301 increased sympathetic activity [pe]
+302 imidazolines [chemical/ingredient]
+303 calcineurin inhibitor immunosuppressant [epc]
+304 calcineurin inhibitors [moa]
+305 inhibit ovum fertilization [pe]
+306 progestin-containing intrauterine device [epc]
+307 nitroimidazole antimicrobial [epc]
+308 nitroimidazoles [chemical/ingredient]
+309 opioid agonist [epc]
+310 opioid agonists [moa]
+311 barbiturate [epc]
+312 barbiturates [chemical/ingredient]
+313 decreased prostaglandin production [pe]
+314 platelet aggregation inhibitor [epc]
+315 central nervous system stimulant [epc]
+316 central nervous system stimulation [pe]
+317 methylxanthine [epc]
+318 xanthines [chemical/ingredient]
+319 full opioid agonists [moa]
+320 polymyxin-class antibacterial [epc]
+321 polymyxins [chemical/ingredient]
+322 dihydrofolate reductase inhibitor antibacterial [epc]
+323 dihydrofolate reductase inhibitors [moa]
+324 organic cation transporter 2 inhibitors [moa]
+325 decreased protein synthesis [pe]
+326 decreased histamine release [pe]
+327 mast cell stabilizer [epc]
+328 adrenergic alpha-agonists [moa]
+329 alpha-adrenergic agonist [epc]
+330 adrenergic agonists [moa]
+331 adrenergic receptor agonist [epc]
+332 histamine-1 receptor inhibitor [epc]
+333 ergocalciferols [chemical/ingredient]
+334 provitamin d2 compound [epc]
+335 platinum-based drug [epc]
+336 platinum-containing compounds [chemical/ingredient]
+337 antiseptic [epc]
+338 antirheumatic agent [epc]
+339 antimalarial [epc]
+340 iron [chemical/ingredient]
+341 parenteral iron replacement [epc]
+342 phosphate binder [epc]
+343 phosphate chelating activity [moa]
+344 gamma-aminobutyric acid-ergic agonist [epc]
+345 gaba a agonists [moa]
+346 pyridines [chemical/ingredient]
+347 central nervous system depression [pe]
+348 aminoketone [epc]
+349 dopamine uptake inhibitors [moa]
+350 increased dopamine activity [pe]
+351 increased norepinephrine activity [pe]
+352 granulocyte colony-stimulating factor [chemical/ingredient]
+353 granulocyte-macrophage colony-stimulating factor [chemical/ingredient]
+354 increased myeloid cell production [pe]
+355 leukocyte growth factor [epc]
+356 hematopoietic stem cell mobilizer [epc]
+357 increased hematopoietic stem cell mobilization [pe]
+358 pcsk9 inhibitor [epc]
+359 pcsk9 inhibitors [moa]
+360 interleukin 6 receptor antagonists [moa]
+361 interleukin-6 receptor antagonist [epc]
+362 antidiarrheal [epc]
+363 anticholinergic [epc]
+364 cholinergic antagonists [moa]
+365 gonadotropin releasing hormone receptor agonist [epc]
+366 gonadotropin releasing hormone receptor agonists [moa]
+367 aldosterone antagonist [epc]
+368 aldosterone antagonists [moa]
+369 prostaglandin e1 analog [epc]
+370 prostaglandins e
+371 synthetic [chemical/ingredient]
+372 calcium channel antagonists [moa]
+373 calcium channel blocker [epc]
+374 rna synthetase inhibitor antibacterial [epc]
+375 rna synthetase inhibitors [moa]
+376 progesterone [chemical/ingredient]
+377 progesterone [epc]
+378 vitamin b6 analog [epc]
+379 vitamin b 6 [chemical/ingredient]
+380 analogs/derivatives [chemical/ingredient]
+381 vitamin b 12 [chemical/ingredient]
+382 vitamin b12 [epc]
+383 blood coagulation factor [epc]
+384 increased coagulation factor activity [pe]
+385 calcium [chemical/ingredient]
+386 cations
+387 divalent [chemical/ingredient]
+388 anti-epileptic agent [epc]
+389 decreased central nervous system disorganized electrical activity [pe]
+390 cannabinoid [epc]
+391 cannabinoids [chemical/ingredient]
+392 centrally-mediated muscle relaxation [pe]
+393 muscle relaxant [epc]
+394 increased diuresis at loop of henle [pe]
+395 loop diuretic [epc]
+396 calcium [epc]
+397 oxidation-reduction agent [epc]
+398 oxidation-reduction activity [moa]
+399 stimulation large intestine fluid/electrolyte secretion [pe]
+400 potassium compounds [chemical/ingredient]
+401 potassium salt [epc]
+402 penicillin-class antibacterial [epc]
+403 penicillins [chemical/ingredient]
+404 beta lactamase inhibitors [moa]
+405 beta lactamase inhibitor [epc]
+406 antiemetic [epc]
+407 emesis suppression [pe]
+408 azole antifungal [epc]
+409 azoles [chemical/ingredient]
+410 cytochrome p450 2c19 inhibitors [moa]
+411 cytochrome p450 2c9 inhibitors [moa]
+412 decreased gnrh secretion [pe]
+413 gonadotropin releasing hormone antagonist [epc]
+414 gonadotropin releasing hormone receptor antagonists [moa]
+415 gonadotropin [epc]
+416 gonadotropins [chemical/ingredient]
+417 neuromuscular nondepolarizing blockade [pe]
+418 nondepolarizing neuromuscular blocker [epc]
+419 live attenuated bacillus calmette-guerin vaccine [epc]
+420 bcg vaccine [chemical/ingredient]
+421 live attenuated bacillus calmette-guerin immunotherapy [epc]
+422 increased macrophage proliferation [pe]
+423 increased immunologically active molecule activity [pe]
+424 factor viii activator [epc]
+425 increased coagulation factor viii activity [pe]
+426 increased coagulation factor viii concentration [pe]
+427 vasopressin analog [epc]
+428 vasopressins [chemical/ingredient]
+429 human serum albumin [epc]
+430 increased intravascular volume [pe]
+431 increased oncotic pressure [pe]
+432 serum albumin [chemical/ingredient]
+433 cholecalciferol [chemical/ingredient]
+434 vitamin d3 analog [epc]
+435 mood stabilizer [epc]
+436 phosphodiesterase 3 inhibitor [epc]
+437 phosphodiesterase 3 inhibitors [moa]
+438 macrolide antimicrobial [epc]
+439 macrolides [chemical/ingredient]
+440 cardiac glycoside [epc]
+441 cardiac glycosides [chemical/ingredient]
+442 serotonin 3 receptor antagonists [moa]
+443 serotonin-3 receptor antagonist [epc]
+444 gamma-aminobutyric acid a receptor agonist [epc]
+445 cholinesterase inhibitor [epc]
+446 cholinesterase inhibitors [moa]
+447 dihydropyridine calcium channel blocker [epc]
+448 dihydropyridines [chemical/ingredient]
+449 herpes simplex virus nucleoside analog dna polymerase inhibitor [epc]
+450 herpes zoster virus nucleoside analog dna polymerase inhibitor [epc]
+451 herpesvirus nucleoside analog dna polymerase inhibitor [epc]
+452 partial opioid agonist [epc]
+453 partial opioid agonists [moa]
+454 opioid antagonist [epc]
+455 opioid antagonists [moa]
+456 tricyclic antidepressant [epc]
+457 cholinergic muscarinic agonists [moa]
+458 cholinergic receptor agonist [epc]
+459 vitamin d2 analog [epc]
+460 acetyl aldehyde dehydrogenase inhibitors [moa]
+461 aldehyde dehydrogenase inhibitor [epc]
+462 amphetamine anorectic [epc]
+463 amphetamines [chemical/ingredient]
+464 appetite suppression [pe]
+465 human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor [epc]
+466 non-nucleoside analog [chemical/ingredient]
+467 non-nucleoside reverse transcriptase inhibitors [moa]
+468 cytochrome p450 3a inducers [moa]
+469 cytochrome p450 2b6 inducers [moa]
+470 amide local anesthetic [epc]
+471 amides [chemical/ingredient]
+472 local anesthesia [pe]
+473 competitive opioid antagonists [moa]
+474 opioid agonist/antagonist [epc]
+475 acidifying activity [moa]
+476 folate analog [epc]
+477 folic acid [chemical/ingredient]
+478 vitamin k antagonist [epc]
+479 vitamin k inhibitors [moa]
+480 cholinergic agonists [moa]
+481 diagnostic dye [epc]
+482 dyes [moa]
+483 alpha-1 adrenergic agonist [epc]
+484 adrenergic alpha1-agonists [moa]
+485 polyene antimicrobial [epc]
+486 polyenes [chemical/ingredient]
+487 ester local anesthetic [epc]
+488 esters [chemical/ingredient]
+489 calculi dissolution agent [epc]
+490 magnesium ion exchange activity [moa]
+491 inhibition small intestine fluid/electrolyte absorption [pe]
+492 rifamycin antibacterial [epc]
+493 general anesthesia [pe]
+494 general anesthetic [epc]
+495 heparin [chemical/ingredient]
+496 unfractionated heparin [epc]
+497 microtubule inhibition [pe]
+498 microtubule inhibitor [epc]
+499 purine antimetabolite [epc]
+500 benzodiazepine antagonist [epc]
+501 hydrolytic lysosomal glucocerebroside-specific enzyme [epc]
+502 glucosylceramidase [chemical/ingredient]
+503 typical antipsychotic [epc]
+504 histamine h2 receptor antagonists [moa]
+505 histamine-2 receptor antagonist [epc]
+506 decreased tracheobronchial stretch receptor activity [pe]
+507 non-narcotic antitussive [epc]
+508 receptor tyrosine kinase inhibitors [moa]
+509 kinase inhibitors [moa]
+510 heparin
+511 low-molecular-weight [chemical/ingredient]
+512 low molecular weight heparin [epc]
+513 partial cholinergic nicotinic agonist [epc]
+514 partial cholinergic nicotinic agonists [moa]
+515 janus kinase inhibitor [epc]
+516 janus kinase inhibitors [moa]
+517 ccr5 co-receptor antagonist [epc]
+518 chemokine co-receptor 5 antagonists [moa]
+519 glycopeptide antibacterial [epc]
+520 glycopeptides [chemical/ingredient]
+521 antihistamine [epc]
+522 histamine receptor antagonists [moa]
+523 cytochrome p450 1a2 inducers [moa]
+524 cytochrome p450 2c8 inducers [moa]
+525 cytochrome p450 2c19 inducers [moa]
+526 cytochrome p450 2d6 inducers [moa]
+527 cytochrome p450 2b6 inhibitors [moa]
+528 organic cation transporter 1 inhibitors [moa]
+529 monoamine oxidase inhibitor [epc]
+530 monoamine oxidase inhibitors [moa]
+531 nitrate vasodilator [epc]
+532 nitrates [chemical/ingredient]
+533 vasodilation [pe]
+534 peroxisome proliferator receptor alpha agonist [epc]
+535 peroxisome proliferator-activated receptor alpha agonists [moa]
+536 ppar alpha [chemical/ingredient]
+537 interleukin 2 receptor antagonists [moa]
+538 interleukin 2 receptor-directed antibody interactions [moa]
+539 interleukin-2 receptor blocking antibody [epc]
+540 udp glucuronosyltransferases inducers [moa]
+541 bcl-2 inhibitor [epc]
+542 increased cellular death [pe]
+543 alveolar surface tension reduction [pe]
+544 surfactant [epc]
+545 surfactant activity [moa]
+546 nicotinic acid [epc]
+547 nicotinic acids [chemical/ingredient]
+548 l-thyroxine [epc]
+549 thyroxine [chemical/ingredient]
+550 benzothiazole [epc]
+551 benzothiazoles [chemical/ingredient]
+552 ammonium ion binding activity [moa]
+553 nitrogen binding agent [epc]
+554 allylamine [chemical/ingredient]
+555 allylamine antifungal [epc]
+556 somatostatin analog [epc]
+557 somatostatin receptor agonists [moa]
+558 catechol o-methyltransferase inhibitors [moa]
+559 catechol-o-methyltransferase inhibitor [epc]
+560 glinide [epc]
+561 potassium channel antagonists [moa]
+562 decreased blood pressure [pe]
+563 iron chelating activity [moa]
+564 iron chelator [epc]
+565 cytochrome p450 1a2 inhibitors [moa]
+566 renin inhibitor [epc]
+567 renin inhibitors [moa]
+568 sphingosine 1-phosphate receptor modulators [moa]
+569 sphingosine 1-phosphate receptor modulator [epc]
+570 adrenergic beta2-agonists [moa]
+571 beta2-adrenergic agonist [epc]
+572 tyrosine kinase inhibitors [moa]
+573 hedgehog pathway inhibitor [epc]
+574 smoothened receptor antagonists [moa]
+575 neprilysin inhibitor [epc]
+576 neprilysin inhibitors [moa]
+577 cd20-directed cytolytic antibody [epc]
+578 cd20-directed antibody interactions [moa]
+579 organic anion transporter 1 inhibitors [moa]
+580 organic anion transporter 3 inhibitors [moa]
+581 cytochrome p450 3a5 inhibitors [moa]
+582 acetylcholine releasing agent [epc]
+583 increased acetylcholine activity [pe]
+584 interferon alfa-2b [chemical/ingredient]
+585 interferon-alpha [chemical/ingredient]
+586 androgen receptor antagonists [moa]
+587 androgen receptor inhibitor [epc]
+588 polyene antifungal [epc]
+589 cardiac rhythm alteration [pe]
+590 cephalosporin antibacterial [epc]
+591 cephalosporins [chemical/ingredient]
+592 peroxisome proliferator receptor gamma agonist [epc]
+593 peroxisome proliferator-activated receptor activity [moa]
+594 ppar gamma [chemical/ingredient]
+595 thiazolidinedione [epc]
+596 thiazolidinediones [chemical/ingredient]
+597 sympathomimetic amine anorectic [epc]
+598 nitrofuran antibacterial [epc]
+599 nitrofurans [chemical/ingredient]
+600 dopamine d2 antagonists [moa]
+601 dopamine-2 receptor antagonist [epc]
+602 aluminum complex [epc]
+603 organometallic compounds [chemical/ingredient]
+604 adrenergic alpha2-agonists [moa]
+605 central alpha-2 adrenergic agonist [epc]
+606 tetracycline-class drug [epc]
+607 blood viscosity reducer [epc]
+608 hematologic activity alteration [pe]
+609 fatty acids
+610 omega-3 [chemical/ingredient]
+611 omega-3 fatty acid [epc]
+612 ergolines [chemical/ingredient]
+613 ergot derivative [epc]
+614 inhibition gastric acid secretion [pe]
+615 phenothiazine [epc]
+616 phenothiazines [chemical/ingredient]
+617 decreased cholesterol absorption [pe]
+618 dietary cholesterol absorption inhibitor [epc]
+619 vitamin d analog [epc]
+620 bile acid [epc]
+621 bile acids and salts [chemical/ingredient]
+622 adrenergic beta-agonists [moa]
+623 beta-adrenergic agonist [epc]
+624 catecholamine [epc]
+625 catecholamines [chemical/ingredient]
+626 influenza a m2 protein inhibitor [epc]
+627 m2 protein inhibitors [moa]
+628 decreased striated muscle contraction [pe]
+629 decreased striated muscle tone [pe]
+630 skeletal muscle relaxant [epc]
+631 decreased cell wall integrity [pe]
+632 decreased coagulation factor activity [pe]
+633 calcium chelating activity [moa]
+634 sulfonamide antimicrobial [epc]
+635 thyroid hormone synthesis inhibitor [epc]
+636 thyroid hormone synthesis inhibitors [moa]
+637 ergotamine derivative [epc]
+638 ergotamines [chemical/ingredient]
+639 p-glycoprotein interactions [moa]
+640 xanthine oxidase inhibitor [epc]
+641 xanthine oxidase inhibitors [moa]
+642 purines [chemical/ingredient]
+643 increased uterine smooth muscle contraction or tone [pe]
+644 oxytocic [epc]
+645 oxytocin [chemical/ingredient]
+646 sympathomimetic-like agent [epc]
+647 macrolide [epc]
+648 decreased dna replication [pe]
+649 decreased rna replication [pe]
+650 protein synthesis inhibitors [moa]
+651 increased cytokine activity [pe]
+652 increased cytokine production [pe]
+653 interferon inducers [moa]
+654 recombinant human growth hormone [epc]
+655 recombinant human growth hormones [chemical/ingredient]
+656 gaba b agonists [moa]
+657 decreased platelet production [pe]
+658 platelet-reducing agent [epc]
+659 prostacycline vasodilator [epc]
+660 prostaglandins i [chemical/ingredient]
+661 neuraminidase inhibitor [epc]
+662 neuraminidase inhibitors [moa]
+663 potassium channel openers [moa]
+664 potassium channel opener [epc]
+665 interleukin-5 antagonist [epc]
+666 interleukin-5 antagonists [moa]
+667 urease inhibitor [epc]
+668 urease inhibitors [moa]
+669 cystine disulfide reduction [moa]
+670 n-substituted glycines [chemical/ingredient]
+671 reducing and complexing thiol [epc]
+672 thiazide-like diuretic [epc]
+673 l-triiodothyronine [epc]
+674 triiodothyronine [chemical/ingredient]
+675 dihydrofolate reductase inhibitor antimalarial [epc]
+676 increased prothrombin activity [pe]
+677 reversed anticoagulation activity [pe]
+678 vitamin k [chemical/ingredient]
+679 vitamin k [epc]
+680 warfarin reversal agent [epc]
+681 phenylalanine hydroxylase activators [moa]
+682 interleukin-17 receptor a antagonist [epc]
+683 interleukin 17 receptor a antagonists [moa]
+684 monoamine oxidase type b inhibitor [epc]
+685 monoamine oxidase-b inhibitors [moa]
+686 photoabsorption [moa]
+687 photoactivated radical generator [epc]
+688 photosensitizing activity [pe]
+689 psoralen [epc]
+690 psoralens [chemical/ingredient]
+691 metal chelating activity [moa]
+692 metal chelator [epc]
+693 nucleoside analog antifungal [epc]
+694 decreased parasympathetic acetylcholine activity [pe]
+695 gi motility alteration [pe]
+696 digestive/gi system activity alteration [pe]
+697 vasodilator [epc]
+698 photoenhancer [epc]
+699 calcitonin [chemical/ingredient]
+700 calcitonin [epc]
+701 non-standardized plant allergenic extract [epc]
+702 non-standardized food allergenic extract [epc]
+703 dietary proteins [chemical/ingredient]
+704 plant proteins [chemical/ingredient]
+705 food additives [chemical/ingredient]
+706 non-standardized chemical allergen [epc]
+707 glycerol [chemical/ingredient]
+708 amino acid [epc]
+709 amino acids [chemical/ingredient]
+710 plasma volume expander [epc]
+711 starch [chemical/ingredient]
+712 osmotic diuretic [epc]
+713 lipid emulsion [epc]
+714 lipids [chemical/ingredient]
+715 non-standardized pollen allergenic extract [epc]
+716 standardized animal skin allergenic extract [epc]
+717 fur [chemical/ingredient]
+718 standardized insect allergenic extract [epc]
+719 antigens
+720 dermatophagoides [chemical/ingredient]
+721 insect proteins [chemical/ingredient]
+722 non-standardized animal skin allergenic extract [epc]
+723 cells
+724 epidermal [chemical/ingredient]
+725 non-standardized plant fiber allergenic extract [epc]
+726 seed storage proteins [chemical/ingredient]
+727 meat proteins [chemical/ingredient]
+728 non-standardized insect allergenic extract [epc]
+729 non-standardized insect venom allergenic extract [epc]
+730 ant venoms [chemical/ingredient]
+731 non-standardized feather allergenic extract [epc]
+732 feathers [chemical/ingredient]
+733 non-standardized fungal allergenic extract [epc]
+734 fungal proteins [chemical/ingredient]
+735 standardized animal hair allergenic extract [epc]
+736 dander [chemical/ingredient]
+737 salivary proteins and peptides [chemical/ingredient]
+738 non-standardized house dust allergenic extract [epc]
+739 house dust [chemical/ingredient]
+740 nut proteins [chemical/ingredient]
+741 fruit proteins [chemical/ingredient]
+742 vegetable proteins [chemical/ingredient]
+743 grain proteins [chemical/ingredient]
+744 caseins [chemical/ingredient]
+745 poultry proteins [chemical/ingredient]
+746 shellfish proteins [chemical/ingredient]
+747 fish proteins
+748 dietary [chemical/ingredient]
+749 egg proteins
+750 milk proteins [chemical/ingredient]
+751 radiopharmaceutical activity [moa]
+752 cholecystokinin [chemical/ingredient]
+753 cholecystokinin analog [epc]
+754 paramagnetic contrast agent [epc]
+755 digoxin binding activity [moa]
+756 depigmenting activity [pe]
+757 melanin synthesis inhibitor [epc]
+758 melanin synthesis inhibitors [moa]
+759 phosphodiesterase 4 inhibitor [epc]
+760 phosphodiesterase 4 inhibitors [moa]
+761 poly(adp-ribose) polymerase inhibitor [epc]
+762 poly(adp-ribose) polymerase inhibitors [moa]
+763 estrogen receptor antagonist [epc]
+764 estrogen receptor antagonists [moa]
+765 urate transporter 1 inhibitor [epc]
+766 urate transporter 1 inhibitors [moa]
+767 sodium-glucose cotransporter 2 inhibitor [epc]
+768 sodium-glucose transporter 2 inhibitors [moa]
+769 amylin agonists [moa]
+770 amylin analog [epc]
+771 standardized chemical allergen [epc]
+772 irrigation [moa]
+773 human blood coagulation factor [epc]
+774 increased coagulation activity [pe]
+775 blood coagulation factors [chemical/ingredient]
+776 nmda receptor antagonists [moa]
+777 n-methyl-d-aspartate receptor antagonist [epc]
+778 p-glycoprotein inducers [moa]
+779 benzylamine antifungal [epc]
+780 benzylamines [chemical/ingredient]
+781 cystine depleting agent [epc]
+782 local anesthetic [epc]
+783 contrast agent for ultrasound imaging [epc]
+784 ultrasound contrast activity [moa]
+785 lipopeptide antibacterial [epc]
+786 adenosine receptor agonist [epc]
+787 adenosine receptor agonists [moa]
+788 partial opioid agonist/antagonist [epc]
+789 dopaminergic agonist [epc]
+790 antidote [epc]
+791 antidote for acetaminophen overdose [epc]
+792 decreased respiratory secretion viscosity [pe]
+793 increased glutathione concentration [pe]
+794 mucolytic [epc]
+795 reduction activity [moa]
+796 copper absorption inhibitor [epc]
+797 decreased copper ion absorption [pe]
+798 depolarizing neuromuscular blocker [epc]
+799 neuromuscular depolarizing blockade [pe]
+800 tetracycline-class antimicrobial [epc]
+801 guanylate cyclase-c agonist [epc]
+802 guanylate cyclase activators [moa]
+803 beta3-adrenergic agonist [epc]
+804 adrenergic beta3-agonists [moa]
+805 lipid-based polyene antifungal [epc]
+806 decreased mitosis [pe]
+807 tubulin inhibiting agent [epc]
+808 pyrethrins [chemical/ingredient]
+809 pyrethroid [epc]
+810 arteriolar vasodilation [pe]
+811 arteriolar vasodilator [epc]
+812 carnitine [chemical/ingredient]
+813 carnitine analog [epc]
+814 cholinergic muscarinic agonist [epc]
+815 adrenocorticotropic hormone [chemical/ingredient]
+816 adrenocorticotropic hormone [epc]
+817 endoglycosidase [epc]
+818 glycoside hydrolases [chemical/ingredient]
+819 human immunoglobulin g [epc]
+820 passively acquired immunity [pe]
+821 endogenous antigen neutralization [moa]
+822 uncompetitive n-methyl-d-aspartate receptor antagonist [epc]
+823 sigma-1 agonist [epc]
+824 uncompetitive nmda receptor antagonists [moa]
+825 sigma-1 receptor agonists [moa]
+826 antihypoglycemic agent [epc]
+827 gastrointestinal motility inhibitor [epc]
+828 increased gluconeogenesis [pe]
+829 increased glycogenolysis [pe]
+830 decreased gi smooth muscle tone [pe]
+831 decreased gi motility [pe]
+832 decreased glycolysis [pe]
+833 humanized monoclonal antibody fragment [epc]
+834 monoclonal
+835 humanized [chemical/ingredient]
+836 vitamin a [chemical/ingredient]
+837 vitamin a [epc]
+838 increased medullary respiratory drive [pe]
+839 respiratory stimulant [epc]
+840 copper [chemical/ingredient]
+841 copper-containing intrauterine device [epc]
+842 decreased embryonic implantation [pe]
+843 decreased sperm motility [pe]
+844 autonomic ganglionic blocker [epc]
+845 decreased autonomic ganglionic activity [pe]
+846 antigen neutralization [moa]
+847 human alpha-1 proteinase inhibitor [epc]
+848 trypsin inhibitors [moa]
+849 asparaginase [chemical/ingredient]
+850 asparagine-specific enzyme [epc]
+851 5-lipoxygenase inhibitor [epc]
+852 5-lipoxygenase inhibitors [moa]
+853 decreased leukotriene production [pe]
+854 potassium channel blocker [epc]
+855 glucosylceramide synthase inhibitor [epc]
+856 glucosylceramide synthase inhibitors [moa]
+857 oxaborole antifungal [epc]
+858 boron compounds [chemical/ingredient]
+859 cholinesterase reactivator [epc]
+860 cholinesterase reactivators [moa]
+861 inhalation diagnostic agent [epc]
+862 inactivated clostridium tetani vaccine [epc]
+863 tetanus toxoid [chemical/ingredient]
+864 inactivated corynebacterium diphtheriae vaccine [epc]
+865 diphtheria toxoid [chemical/ingredient]
+866 human immunoglobulin [epc]
+867 virus neutralization [moa]
+868 virus-specific hyperimmune globulins [chemical/ingredient]
+869 norepinephrine releasing agent [epc]
+870 pleuromutilin [chemical/ingredient]
+871 pleuromutilin antibacterial [epc]
+872 chloride channel activator [epc]
+873 chloride channel activators [moa]
+874 bee venoms [chemical/ingredient]
+875 standardized insect venom allergenic extract [epc]
+876 radioactive therapeutic agent [epc]
+877 increased prostaglandin activity [pe]
+878 n-calcium channel receptor antagonists [moa]
+879 n-type calcium channel antagonist [epc]
+880 melatonin receptor agonist [epc]
+881 melatonin receptor agonists [moa]
+882 demulcent [epc]
+883 demulcent activity [moa]
+884 proteolytic enzyme [epc]
+885 peptide hydrolases [chemical/ingredient]
+886 catecholamine synthesis inhibitor [epc]
+887 catecholamine synthesis inhibitors [moa]
+888 complement inhibitor [epc]
+889 complement inhibitors [moa]
+890 hydrolytic lysosomal cholesteryl ester-specific enzyme [epc]
+891 hydrolytic lysosomal triacylglycerol-specific enzyme [epc]
+892 lysosomal acid cholesterol esterase [chemical/ingredient]
+893 tissue-nonspecific alkaline phosphatase [epc]
+894 alkaline phosphatase [chemical/ingredient]
+895 autologous cellular immunotherapy [epc]
+896 cultured
+897 autologous [chemical/ingredient]
+898 peripheral blood mononuclear cells [chemical/ingredient]
+899 vesicular monoamine transporter 2 inhibitor [epc]
+900 vesicular monoamine transporter 2 inhibitors [moa]
+901 inactivated influenza a virus vaccine [epc]
+902 influenza vaccines [chemical/ingredient]
+903 silk [chemical/ingredient]
+904 skin test antigen [epc]
+905 tuberculosis skin test [epc]
+906 bacterial [chemical/ingredient]
+907 human c1 esterase inhibitor [epc]
+908 decreased vascular permeability [pe]
+909 kallikrein inhibitors [moa]
+910 interferon gamma [epc]
+911 interferon-gamma [chemical/ingredient]
+912 inactivated japanese encephalitis virus vaccine [epc]
+913 japanese encephalitis vaccines [chemical/ingredient]
+914 allogeneic cultured cell scaffold [epc]
+915 collagen [chemical/ingredient]
+916 tissue scaffolds [chemical/ingredient]
+917 allogeneic [chemical/ingredient]
+918 fibroblasts [chemical/ingredient]
+919 keratinocytes [chemical/ingredient]
+920 recombinant antithrombin [epc]
+921 anti-anginal [epc]
+922 live attenuated influenza a virus vaccine [epc]
+923 interferon-beta [chemical/ingredient]
+924 recombinant human interferon beta [epc]
+925 recombinant proteins [chemical/ingredient]
+926 parathyroid hormone [epc]
+927 sclerosing agent [epc]
+928 sclerosing activity [moa]
+929 vascular sclerosing activity [pe]
+930 plasma kallikrein inhibitor [epc]
+931 inactivated bordetella pertussis vaccine [epc]
+932 pertussis vaccine [chemical/ingredient]
+933 inactivated poliovirus vaccine [epc]
+934 poliovirus vaccine [chemical/ingredient]
+935 inactivated meningococcal vaccine [epc]
+936 meningococcal vaccines [chemical/ingredient]
+937 inactivated salmonella typhi vaccine [epc]
+938 typhoid [chemical/ingredient]
+939 vi polysaccharide vaccine
+940 live attenuated yellow fever virus vaccine [epc]
+941 yellow fever vaccine [chemical/ingredient]
+942 non-standardized bacterial allergenic extract [epc]
+943 bacterial proteins [chemical/ingredient]
+944 non-standardized animal hair allergenic extract [epc]
+945 decreased b lymphocyte activation [pe]
+946 b lymphocyte stimulator-specific inhibitor [epc]
+947 b lymphocyte stimulator-directed antibody interactions [moa]
+948 anthrax protective antigen-directed antibody [epc]
+949 anthrax protective antigen-directed antibody interactions [moa]
+950 multidrug and toxin extrusion transporter 1 inhibitors [moa]
+951 methylated sulfonamide antibacterial [epc]
+952 methylated sulfonamides [chemical/ingredient]
+953 selective progesterone receptor modulators [moa]
+954 progesterone agonist/antagonist [epc]
+955 live vaccinia virus vaccine [epc]
+956 smallpox vaccine [chemical/ingredient]
+957 cell death inducer [epc]
+958 anti-ige [epc]
+959 decreased ige activity [pe]
+960 ige-directed antibody interactions [moa]
+961 vascular endothelial growth factor receptor inhibitors [moa]
+962 vascular endothelial growth factor-directed antibody [epc]
+963 vascular endothelial growth factor-directed antibody interactions [moa]
+964 deoxyribonuclease i [chemical/ingredient]
+965 recombinant human deoxyribonuclease 1 [epc]
+966 pyridone [epc]
+967 pyridones [chemical/ingredient]
+968 her2 receptor antagonist [epc]
+969 her2/neu/cerbb2 antagonists [moa]
+970 antibodies [chemical/ingredient]
+971 radioactive alpha-particle emitting therapeutic agent [epc]
+972 alpha-particle emitting activity [moa]
+973 guanylate cyclase stimulators [moa]
+974 soluble guanylate cyclase stimulator [epc]
+975 antihelminthic [epc]
+976 glycosaminoglycan [epc]
+977 glycosaminoglycans [chemical/ingredient]
+978 epoxide hydrolase inhibitors [moa]
+979 collagenases [chemical/ingredient]
+980 collagen-specific enzyme [epc]
+981 human platelet-derived growth factor [epc]
+982 platelet-derived growth factor [chemical/ingredient]
+983 antivenin [epc]
+984 venom neutralization [moa]
+985 antivenins [chemical/ingredient]
+986 carboxypeptidase [epc]
+987 carboxypeptidases [chemical/ingredient]
+988 cd30-directed antibody interactions [moa]
+989 cd30-directed immunoconjugate [epc]
+990 immunoconjugates [chemical/ingredient]
+991 cystic fibrosis transmembrane conductance regulator potentiator [epc]
+992 chloride channel activation potentiators [moa]
+993 lead chelating activity [moa]
+994 lead chelator [epc]
+995 macrolide antibacterial [epc]
+996 cytochrome p450 1a inducers [moa]
+997 lipoglycopeptide antibacterial [epc]
+998 lipoglycopeptides [chemical/ingredient]
+999 carbamoyl phosphate synthetase 1 activator [epc]
+1000 carbamoyl phosphate synthetase 1 activators [moa]
+1001 methylating activity [moa]
+1002 methylating agent [epc]
+1003 wasp venoms [chemical/ingredient]
+1004 potassium binder [epc]
+1005 potassium ion binding activity [moa]
+1006 calcium-sensing receptor agonist [epc]
+1007 increased calcium-sensing receptor sensitivity [moa]
+1008 lymphocyte function-associated antigen-1 antagonist [epc]
+1009 lymphocyte function-associated antigen-1 antagonists [moa]
+1010 alpha-glucosidases [chemical/ingredient]
+1011 hydrolytic lysosomal glycosaminoglycan-specific enzyme [epc]
+1012 bradykinin b2 receptor antagonist [epc]
+1013 bradykinin b2 receptor antagonists [moa]
+1014 urate oxidase [chemical/ingredient]
+1015 uric acid-specific enzyme [epc]
+1016 aromatic amino acid decarboxylation inhibitor [epc]
+1017 dopa decarboxylase inhibitors [moa]
+1018 ketolide antibacterial [epc]
+1019 ketolides [chemical/ingredient]
+1020 heparin binding activity [moa]
+1021 heparin reversal agent [epc]
+1022 actinomycin [epc]
+1023 free radical scavenging activity [moa]
+1024 rank ligand inhibitor [epc]
+1025 rank ligand blocking activity [moa]
+1026 hyperpolarization-activated cyclic nucleotide-gated channel blocker [epc]
+1027 hyperpolarization-activated cyclic nucleotide-gated channel antagonists [moa]
+1028 adenosine deaminase [chemical/ingredient]
+1029 bovine intestinal adenosine deaminase [epc]
+1030 interleukin-12 antagonist [epc]
+1031 interleukin-12 antagonists [moa]
+1032 interleukin-23 antagonist [epc]
+1033 interleukin-23 antagonists [moa]
+1034 cytochrome p450 17a1 inhibitors [moa]
+1035 cytochrome p450 17a1 inhibitor [epc]
+1036 interleukin-6 antagonist [epc]
+1037 interleukin-6 antagonists [moa]
+1038 cd38-directed cytolytic antibody [epc]
+1039 cd38-directed antibody interactions [moa]
+1040 decorporation agent [epc]
+1041 ion exchange activity [moa]
+1042 chelating activity [moa]
+1043 thyroid stimulating hormone [epc]
+1044 thyrotropin [chemical/ingredient]
+1045 hydrolytic lysosomal neutral glycosphingolipid-specific enzyme [epc]
+1046 hydrolytic lysosomal glycogen-specific enzyme [epc]
+1047 apolipoprotein b-100 synthesis inhibitor [epc]
+1048 antisense oligonucleotide [epc]
+1049 oligonucleotides
+1050 antisense [chemical/ingredient]
+1051 cd52-directed antibody interactions [moa]
+1052 cd52-directed cytolytic antibody [epc]
+1053 pyrimidine synthesis inhibitor [epc]
+1054 dihydroorotate dehydrogenase inhibitors [moa]
+1055 autologous cultured cell [epc]
+1056 chondrocytes [chemical/ingredient]
+1057 bismuth [chemical/ingredient]
+1058 bismuth [epc]
+1059 vasopressin v2 receptor antagonist [epc]
+1060 vasopressin v2 receptor antagonists [moa]
+1061 decreased immunologically active molecule activity [pe]
+1062 thalidomide analog [epc]
+1063 fungal [chemical/ingredient]
+1064 cd3 blocker immunosuppressant [epc]
+1065 cd3 receptor antagonists [moa]
+1066 cd3-directed antibody interactions [moa]
+1067 diarylquinoline antimycobacterial [epc]
+1068 diarylquinolines [chemical/ingredient]
+1069 fusion protein inhibitors [moa]
+1070 respiratory syncytial virus anti-f protein monoclonal antibody [epc]
+1071 angiotensin 2 type 1 receptor antagonists [moa]
+1072 cytolytic agent [epc]
+1073 decreased cell membrane integrity [pe]
+1074 streptogramin antibacterial [epc]
+1075 streptogramins [chemical/ingredient]
+1076 antileishmanial [epc]
+1077 mu-opioid receptor agonist [epc]
+1078 opioid mu-receptor agonists [moa]
+1079 endothelin receptor antagonist [epc]
+1080 endothelin receptor antagonists [moa]
+1081 hepatitis c virus nucleotide analog ns5b polymerase inhibitor [epc]
+1082 rna replicase inhibitors [moa]
+1083 organic anion transporting polypeptide 2b1 inhibitors [moa]
+1084 noncompetitive ampa glutamate receptor antagonist [epc]
+1085 ampa receptor antagonists [moa]
+1086 serotonin-2c receptor agonist [epc]
+1087 serotonin 2c receptor agonists [moa]
+1088 proteasome inhibitor [epc]
+1089 proteasome inhibitors [moa]
+1090 amphenicol-class antibacterial [epc]
+1091 amphenicols [chemical/ingredient]
+1092 deoxyuridine [chemical/ingredient]
+1093 integrin receptor antagonist [epc]
+1094 integrin receptor antagonists [moa]
+1095 survival motor neuron-2-directed rna interaction [epc]
+1096 increased protein synthesis [pe]
+1097 live attenuated bacillus anthracis vaccine [epc]
+1098 anthrax vaccines [chemical/ingredient]
+1099 thymidine phosphorylase inhibitor [epc]
+1100 thymidine phosphorylase inhibitors [moa]
+1101 non-standardized animal dander allergenic extract [epc]
+1102 increased lymphocyte activation [pe]
+1103 increased lymphocyte cell production [pe]
+1104 interleukin-2 [chemical/ingredient]
+1105 lymphocyte growth factor [epc]
+1106 quaternary ammonium compounds [chemical/ingredient]
+1107 natriuretic peptide [epc]
+1108 natriuretic peptides [chemical/ingredient]
+1109 prostacycline [epc]
+1110 prostacyclin receptor agonist [epc]
+1111 prostacyclin receptor agonists [moa]
+1112 vasopressin receptor antagonists [moa]
+1113 vasopressin receptor antagonist [epc]
+1114 glycolipid disialoganglioside-directed antibody [epc]
+1115 glycolipid disialoganglioside-directed antibody interactions [moa]
+1116 hydroxyphenyl-pyruvate dioxygenase inhibitor [epc]
+1117 hydroxyphenylpyruvate dioxygenase inhibitors [moa]
+1118 fibroblast growth factor 7 [chemical/ingredient]
+1119 increased epithelial proliferation [pe]
+1120 mucocutaneous epithelial cell growth factor [epc]
+1121 interleukin 1 receptor antagonists [moa]
+1122 interleukin-1 receptor antagonist [epc]
+1123 increased blood pressure [pe]
+1124 human antihemophilic factor [epc]
+1125 factor viii [chemical/ingredient]
+1126 increased platelet aggregation [pe]
+1127 von willebrand factor [chemical/ingredient]
+1128 sucrose-specific enzyme [epc]
+1129 phenylalanine hydroxylase activator [epc]
+1130 bacterial neurotoxin neutralization [moa]
+1131 antitoxins [chemical/ingredient]
+1132 central nervous system depressant [epc]
+1133 decreased central nervous system organized electrical activity [pe]
+1134 oligonucleotides [chemical/ingredient]
+1135 aptamers
+1136 nucleotide [chemical/ingredient]
+1137 glp-2 analog [epc]
+1138 glucagon-like peptide-2 (glp-2) agonists [moa]
+1139 glucagon-like peptide 2 [chemical/ingredient]
+1140 live attenuated salmonella typhi vaccine [epc]
+1141 pyrimidine analog [epc]
+1142 pyrimidines [chemical/ingredient]
+1143 farnesoid x receptor agonist [epc]
+1144 farnesoid x receptor agonists [moa]
+1145 inactivated influenza b virus vaccine [epc]
+1146 porphyrin precursor [epc]
+1147 porphyrinogens [chemical/ingredient]
+1148 fluoroquinolone antibacterial [epc]
+1149 fluoroquinolones [chemical/ingredient]
+1150 pyrophosphate analog [chemical/ingredient]
+1151 pyrophosphate analog dna polymerase inhibitor [epc]
+1152 adrenal steroid synthesis inhibitor [epc]
+1153 adrenal steroid synthesis inhibitors [moa]
+1154 progestational hormone receptor antagonists [moa]
+1155 progestin antagonist [epc]
+1156 microsomal triglyceride transfer protein inhibitor [epc]
+1157 microsomal triglyceride transfer protein inhibitors [moa]
+1158 leptin analog [epc]
+1159 leptin [chemical/ingredient]
+1160 allogeneic cord blood hematopoietic progenitor cell therapy [epc]
+1161 hematopoietic stem cells [chemical/ingredient]

raw/README.txt

@@ -0,0 +1,14 @@
+This dataset consists of the pharmaceutical classes used to classify drugs in
+the National Drug Code Directory maintained by the Food and Drug
+Administration. The original data was downloaded from
+https://www.fda.gov/Drugs/InformationOnDrugs/ucm142438.htm. Each simplex
+corresponds to an NDC code for a drug, where the nodes are the classes applied
+to the drug.  Timestamps are in days and represent when the drug was first
+marketed. Note that the same drug substance can have more than one NDC code. For
+example, different dosages of the same drug may result in multiple NDC codes.
+
+
+The file NDC-classes-node-labels.txt maps the node IDs to the classes.
+
+The nth line in NDC-classes-simplex-labels.txt is the name of the drug
+corresponding to the nth simplex.